Plant Transcription Factor Database
Previous version: v3.0
Brassica napus
BES1 Family
Species TF ID Description
GSBRNA2T00006083001BES1 family protein
GSBRNA2T00016157001BES1 family protein
GSBRNA2T00026156001BES1 family protein
GSBRNA2T00035564001BES1 family protein
GSBRNA2T00036557001BES1 family protein
GSBRNA2T00037466001BES1 family protein
GSBRNA2T00041155001BES1 family protein
GSBRNA2T00083078001BES1 family protein
GSBRNA2T00083128001BES1 family protein
GSBRNA2T00083129001BES1 family protein
GSBRNA2T00084311001BES1 family protein
GSBRNA2T00093640001BES1 family protein
GSBRNA2T00097012001BES1 family protein
GSBRNA2T00099403001BES1 family protein
GSBRNA2T00100147001BES1 family protein
GSBRNA2T00102875001BES1 family protein
GSBRNA2T00103616001BES1 family protein
GSBRNA2T00106620001BES1 family protein
GSBRNA2T00107743001BES1 family protein
GSBRNA2T00112602001BES1 family protein
GSBRNA2T00116741001BES1 family protein
GSBRNA2T00121507001BES1 family protein
GSBRNA2T00131056001BES1 family protein
GSBRNA2T00131390001BES1 family protein
GSBRNA2T00136887001BES1 family protein
GSBRNA2T00139508001BES1 family protein
GSBRNA2T00146419001BES1 family protein
GSBRNA2T00146920001BES1 family protein
GSBRNA2T00148012001BES1 family protein
GSBRNA2T00151358001BES1 family protein
BES1 Family Introduction

Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J.
A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
Cell. 2005 Jan 28;120(2):249-59.
PMID: 15680330